South Carolina's fertility market is growing, with clinics in Columbia, Charleston, and Greenville. Charleston has become a more prominent fertility hub in recent years, and Greenville has expanded its healthcare offerings. South Carolina has no insurance mandate for IVF.

Use our IVF cost calculator for a personalized estimate, or view IVF costs across all states.

No insurance mandate in South Carolina

South Carolina has no law requiring insurers to cover IVF. Most South Carolina patients pay out of pocket or rely on employer-sponsored fertility benefits. Some large self-insured employers offer fertility coverage regardless of state law — always check with your HR department about your specific plan.

→ Learn more about insurance coverage at RESOLVE.org

IVF costs by city in South Carolina

City / RegionTypical cost per cycleMandate applies?
Columbia$8,500–$14,000No
Charleston$9,000–$14,500No
Greenville$8,500–$13,500No
North Charleston$8,500–$13,500No

Costs are base procedure estimates. Add $3,000–$6,000 for medications if billed separately.

South Carolina vs. national average

MarketCost per cycleInsurance mandate
South Carolina$8,500–$14,500No mandate
National average$11,000–$14,000Varies by state

Calculate your South Carolina IVF cost

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4 CDC-Verified IVF Clinics in South Carolina

4 IVF clinics 4 offer egg freezing 3 offer egg donation 3 offer gestational carrier

All clinics below report annual outcome data to the CDC under the Fertility Clinic Success Rate and Certification Act. Data sourced from CDC's 2022 ART Fertility Clinic Success Rates Report. Success rates vary by patient age, diagnosis, and treatment protocol and should not be used to compare clinics.

Adore Fertility
Medical Director: Jeris Cox, MD
✓ CDC Reporting Clinic
📍 1280 Hospital Drive, Suite 300, Mount Pleasant, SC 29464
IVFEgg FreezingFrozen Transfer
Annual cycles: 75  |  Live birth rate (under 35): 0.0% (CDC 2022)
Coastal Fertility Specialists
Medical Director: John A. Schnorr, MD
✓ CDC Reporting Clinic
📍 1375 Hospital Dr, Mount Pleasant, SC 29464
IVFEgg FreezingEgg DonationFrozen TransferGestational Carrier
Annual cycles: 1655  |  Live birth rate (under 35): 65.2% (CDC 2022)
Fertility Center of the Carolinas, University Medical Group, Department of Obstetrics and Gynecology
Medical Director: Creighton E. Likes, MD
✓ CDC Reporting Clinic
📍 890 W. Faris Rd, Suite 470, Greenville, SC 29605
IVFEgg FreezingEgg DonationFrozen TransferGestational Carrier
Annual cycles: 605  |  Live birth rate (under 35): 39.5% (CDC 2022)
Piedmont Reproductive Endocrinology Group, PA
Medical Director: John E. Nichols, MD
✓ CDC Reporting Clinic
📍 17 Caledon Ct, Suite C, Greenville, SC 29615
IVFEgg FreezingEgg DonationFrozen TransferGestational Carrier
Annual cycles: 1807  |  Live birth rate (under 35): 47.8% (CDC 2022)

Data source: CDC National ART Surveillance System (NASS) 2022 Report via cdc.gov/art/success-rates. Contact clinics directly to verify current services, pricing, and insurance acceptance.

Frequently asked questions

IVF in South Carolina typically costs $8,500–$14,500 per cycle. Charleston and Columbia have the most established fertility clinics in the state.

South Carolina has no state mandate requiring insurance coverage of IVF. Most patients pay out of pocket or rely on employer-sponsored fertility benefits.

Charleston and Columbia have the top fertility programs in South Carolina. Greenville patients may also consider Charlotte, North Carolina clinics, which are a short drive north and have a larger market.

Compare nearby states

→ IVF Cost in North Carolina → IVF Cost in Georgia → IVF Cost in Tennessee → IVF Cost in Virginia
📊 Data Sources & Methodology

Cost estimates are updated annually. Individual clinic pricing varies. See our full methodology →

Estimates based on published SART, ASRM, and CDC data for South Carolina clinics. Costs vary significantly by clinic and individual protocol. This is not a quote. Always verify costs directly with your clinic.